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Cerca in Study Connect
  • NCT06476808

Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors. - CA231-0000

Aggiornato: 28 maggio, 2025   |   ClinicalTrials.gov.

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SELEZIONI UNA LINGUA

Dettagli della sperimentazione

  • Phase 1

    Fase

  • Sesso

  • 18+

    Fascia d'età

  • 6

    Sede/i

  • Recruiting

Opzioni di trattamento

Bracci dello studio
INTERVENTO ASSEGNATO
Experimental: Arm 1: Dose Escalation
Drug: BMS-986463
Experimental: Arm 2: Dose Expansion
Drug: BMS-986463

Principali criteri di idoneità

Inclusion Criteria - Participants must have an Eastern Cooperative Oncology Group Performance Status of 0 or 1. - Participants must have at least 1 lesion accessible for biopsy in addition to the target lesion, from which a fresh pre treatment biopsy must be obtained. - Participants must have an unresectable/metastatic carcinoma. Exclusion Criteria - Participants must not have Leptomeningeal metastases. - Participants must not have concurrent malignancy (present during screening) requiring treatment or history of prior malignancy active within 2 years prior to treatment. - Participants must not have had any prior radiation therapy within 2 weeks prior to start of study treatment. - Other protocol-defined Inclusion/Exclusion criteria apply.

Ti consigliamo vivamente di contattare BMS per segnalare gli effetti collaterali (eventi avversi)
Qui vengono definiti gli effetti collaterali (eventi avversi) e altri eventi da segnalare
Segnala effetti collaterali (eventi avversi) o reclami sulla qualità del prodotto: informazioni mediche