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  • NCT06618287

Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors - CA244-0001

Opdateret: 18 december, 2024   |   ClinicalTrials.gov

Udskriftsvenligt sammendrag

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Udskriv denne side CA244-0001
Hente vejledningen til forsøgsdeltagere

VÆLG SPROG

Forsøgsdetaljer

  • Phase 1/Phase 2

    Fase

  • Køn

  • 18+

    Aldersinterval

  • 13

    Beliggenhed(er)

  • Recruiting

Behandlingsmuligheder

Forsøgsgrene
TILDELT INTERVENTION
Experimental: Group A
Drug: BMS-986507, Osimertinib
Experimental: Group B
Drug: BMS-986507, Pembrolizumab

Primære egnethedskriterier

Inclusion Criteria - Participants must have at least one measurable lesion per response evaluation criteria in solid tumors. - Participants must have an Eastern Cooperative Oncology Group Performance Status of 0 or 1. - Participants must have a life expectancy of at least 3 months at the time of the first dose. Exclusion Criteria - Participants must not have any mixed Small Cell Lung Cancer (SCLC) and Non-Small Cell Lung Cancer (NSCLC) histology. - Participants must not have any untreated symptomatic central nervous system (CNS) metastases. - Participants must not have a history of serious recurrent infections. - Participants must not have a history of severe heart disease. - Other protocol-defined Inclusion/Exclusion criteria apply.

Hvis du vil rapportere en bivirkning, kan du indberette direkte til Lægemiddelstyrelsen via hjemmesiden www.meldenbivirkning.dk
Vi anbefaler at du også kontakter BMS for at rapportere bivirkninger.
Bivirkninger og andre rapporterbare begivenheder er defineret her
Rapporter bivirkninger eller klager over produktkvalitet: Medicinsk information

466-DK-2200001